Clinical Significance
1.Prevention of Anemia:
A deficiency in vitamin B12 can lead to megaloblastic anemia, characterized by fatigue, weakness, and neurological symptoms.
2.Neurological Disorders:
B12 deficiency can cause nerve damage, leading to symptoms such as numbness, tingling, memory loss, and difficulty walking.
3.Cognitive Function:
Long-term vitamin B12 deficiency has been linked to cognitive decline and an increased risk of dementia, especially in the elderly.
4.Heart Health:
Adequate levels of vitamin B12 help lower homocysteine levels in the blood, potentially reducing the risk of cardiovascular disease.
Deficiency Symptoms
Symptoms of B12 deficiency include fatigue, weakness, pale skin, memory problems, numbness or tingling in the hands and feet, and difficulty maintaining balance. In severe cases, it can lead to irreversible nerve damage.