Exploring Homocysteine (HCY): A Vital Marker for Cardiovascular Health
At Sekbio, we emphasize the importance of understanding Homocysteine (HCY) as a crucial marker in cardiovascular health. Here’s a comprehensive look at what HCY is and why it matters:
What Is Homocysteine (HCY)?
Homocysteine is an amino acid found in the blood, formed during the metabolism of methionine, another amino acid. Elevated levels of HCY can be an indicator of various health issues, particularly related to heart disease.
Why Is HCY Important?
1. Cardiovascular Risk: High levels of HCY are associated with an increased risk of cardiovascular diseases, including heart attack, stroke, and arterial damage. It’s a key marker for assessing heart health.
2. Vitamin Deficiency: Elevated HCY can be linked to deficiencies in vitamins B6, B12, and folate. These vitamins are essential for converting HCY into other beneficial substances.
3. Genetic Factors: Some people have genetic variations that affect HCY metabolism, making them more susceptible to higher levels and related health risks.
How Is HCY Tested?
A blood test measures the concentration of HCY. This test is often used to:
Assess Risk: Identify individuals at higher risk for cardiovascular diseases.
Monitor Health: Track HCY levels in patients with existing heart conditions or vitamin deficiencies.
Guide Treatment: Adjust treatment plans based on HCY levels and associated risk factors.
Managing HCY Levels
1. Dietary Adjustments：Consuming foods rich in vitamins B6, B12, and folate can help lower HCY levels.
2. Supplements: Vitamin supplements may be recommended if dietary changes are insufficient.
3. Lifestyle Changes: Maintaining a healthy lifestyle, including regular exercise and avoiding
For accurate and reliable HCY testing, we recommend our high-stability, high-performance chemiluminescence bulk reagents HCY assays. Designed to deliver precise results with superior stability, our assays ensure dependable performance, making them ideal for both routine and advanced diagnostic needs.
Our HCY chemiluminescence bulk reagents offer:
l Exceptional Stability: Reliable performance over time, ensuring consistent results.
l High Sensitivity and Specificity: Accurate detection of HCY levels, enhancing diagnostic precision.
| Name | HCY |
| Linear Range | 1~65 μmol/L |
| Sensitivity | 1 μmol/L |
| Correlation | r² =0.9524 |
| Product Code | S00-HCY-AE-T001 |
Linear
| Sample(μmol/L) | dilution ratio | RLU | AVE RLU | C(μmol/L) | |
| 66.72 | 1.0 | 71,357 | 71,898 | 71,628 | 66.72 |
| 53.38 | 0.8 | 82,489 | 83,811 | 83,150 | 56.59 |
| 40.03 | 0.6 | 100,558 | 100,660 | 100,609 | 45.85 |
| 26.69 | 0.4 | 139,411 | 145,330 | 142,371 | 31.14 |
| 13.35 | 0.2 | 264,470 | 273,260 | 268,865 | 14.69 |
| 0.01 | 0 | 1,596,416 | 1,650,864 | 1,623,640 | 0.01 |
Method Comparison
| Competitor Manufacturer | Sekbio RLU | Sekbio Concentration |
| 5.22 | 409,268 | 8.43 |
| 5.75 | 531,752 | 5.47 |
| 5.82 | 468,537 | 6.81 |
| 5.86 | 522,770 | 5.64 |
| 6.1 | 412,497 | 8.33 |
| 6.52 | 445,297 | 7.39 |
| 7.43 | 423,965 | 7.99 |
| 8.95 | 366,143 | 9.94 |
| 9.06 | 342,827 | 10.90 |
| 10.8 | 323,143 | 11.83 |
| 11.1 | 356,997 | 10.30 |
| 11.1 | 301,394 | 12.99 |
| 11.3 | 280,967 | 14.24 |
| 11.9 | 314,975 | 12.25 |
| 14 | 212,297 | 20.17 |
| 14.7 | 223,773 | 18.93 |
| 14.9 | 334,710 | 11.27 |
| 15.9 | 247,082 | 16.76 |
| 19.1 | 233,046 | 18.01 |
| 20.4 | 189,830 | 23.02 |
| 20.5 | 197,503 | 21.97 |
| 23.3 | 180,613 | 24.39 |
| 23.5 | 187,410 | 23.36 |
| 24.3 | 205,909 | 20.91 |
| 24.6 | 192,932 | 22.58 |
| 30.1 | 161,305 | 27.75 |
| 32.3 | 155,621 | 28.90 |
| 36.1 | 144,492 | 31.40 |
| 36.3 | 109,586 | 42.43 |
| 36.3 | 139,192 | 32.72 |
| 38.5 | 110,804 | 41.93 |
| 44 | 100,846 | 46.35 |
| 44.1 | 96,730 | 47.89 |
| 36.5 | 108,591 | 42.14 |
| 38.8 | 107,944 | 42.42 |
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